Intracavitary «in vivo» dosimetry at the high dose rate brachytherapy in oncogynecology

The technology for construction and application of flexible dosimetric assemblies with LiF:Mg,Ti microcrystals (sizes about 0.1 mm) off-line measurements the spatial distribution absorbed dose inside organs at risk (rectum, urethra, vagina) high rate brachytherapy in oncoginecology has been developed. transfer from usage luminescent dosimeters macro sizes (more than 1 to microdosimetrs mm, combination developed protocols estimations using mini-aliquots (10 mg) lu-minescent microdosimeters, provided possibility increase accuracy therapeutic range gynecological malignancies. intracavitary dosimetry a (Ir-129 source) oncogynecology was tested clinic (25 patients). It found that, as rule, measured doses were good agreement calculated areas interest. However, four cases (16% all patients) there an excess local over ones (from 0.6 Gy) urethra rectum (in maximum doses). These may be considered basis monitoring patients’ condition post-therapeutic period. values maximal within acceptable range, recommended by GEC-ESTRO. «in vivo» allows adjust dosimetrical plans multifractional brachytherapy. results clinical approbation show importance this essential element assurance quality oncogynecology.